For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

"This achievement will promote further understanding of the motility mechanism of how the energy of ATP hydrolysis is converted into gliding motility, and how these motors of Mycoplasma mobile are ...

For the first time, scientists have captured the exact moment DNA begins to unravel, shedding light on a fundamental chemical process that enables DNA to serve as the blueprint for life. A recent ...

Credit: Tomoya Tsukazaki The researchers specifically focused on the conformational changes in SecA during the ATP hydrolysis cycle, which is critical to the translocation mechanism. The ...

ATP burning, or hydrolysis, functions like the spring in a mouse trap, snapping the helicase forward and pulling the DNA strands apart." Among the many discoveries made by the KAUST scientists was ...

The researchers specifically focused on the conformational changes in SecA during the ATP hydrolysis cycle, which is critical to the translocation mechanism. The hydrolysis of ATP serves as the ...

The motor domain contains the catalytic site for ATP hydrolysis and the actin or microtubule-binding site. The neck region acts as a lever arm, amplifying the small conformational changes generated by ...