This indicates that BRCA2 variants, somatic and germline, have a major role in prostate cancer progression, affecting at least one in 10 carriers with the disease, say the researchers. BRCA1 ...

Missing from current guidelines is consideration of the role of estrogens for BRCA1/BRCA2 mutation carriers. Potential implications of hormones for risk of cancer and effectiveness of risk ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

Recent investigation focuses on the effects of BRCA1 and BRCA2 tumor pathogenic variants (tPVs) within the parameters of two ...

Susan Domchek, MD, FASCO, has spent her entire career striving to stay one step ahead of cancer.In recognition of her ...

after a five-member panel at the school alleged that he had tampered with data related to the antibody assay he developed to test how BRCA1 encodes a protein to repair DNA damage. His case is now ...