Most cell signals are chemical in nature. For example, prokaryotic organisms have sensors that detect nutrients and help them navigate toward food sources. In multicellular organisms, growth ...

Cellular signaling is an elaborate, dynamic, and interactive system of inter- and intracellular communication, responsible for governing and coordinating activities, from the basic to the complex.

Types of cell signalling pathways include checkpoint signalling, lipid signalling, growth signalling, nutrient signalling, insulin signalling, stress signalling, morphogen signalling, Hippo ...

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, ...

Tsakonas, professor of cell biology, emeritus, in the Blavatnik Institute at Harvard Medical School, has received a ...

This study fills a crucial gap in our understanding of blood cell formation from human pluripotent stem cells (hPSCs). Genome-wide comparisons of hPSC-derived blood progenitor cells with in vivo blood ...

Members of the program engage in research aimed at obtaining a mechanistic understanding of signal transduction and cellular regulation, which includes cellular signaling pathways and downstream ...

Noncanonical signaling involves interactions with other pathways without RBPJ involvement. The NOTCH pathway contributes to resistance by regulating cell survival, apoptosis, and the tumor ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study found that placenta-derived IL1 under ...

The Wingless (Wg) signaling pathway is known to be responsible for one of these constrictions, but until now the underlying mechanism regulating this was not known. "We knew that Wingless ...