Cyclin B1 is relevant in mitosis, a type of cell division. The researchers observed how cyclin B1 docks onto substrates with its pocket and influences the behavior of the kinase as a result.

Press Release Circle Pharma, a clinical-stage biopharmaceutical company focused on developing cell-permeable macrocycle therapeutics, today announced a late-breaking poster presentation at the ...

γ-herpesvirus genomes encode an abundance of homologues of cellular factors, including cyclin and Bcl-2. These viral homologues differ from their cellular counterparts in that the viral proteins ...

Substantial evidence indicates that this is mediated by the rapid activation of cyclin B–Cdk1, which is the core component of M-phase-promoting factor (MPF). This kinase was initially identified ...

"We are excited to outline a clear path for Zentalis to bring azenosertib to patients with Cyclin E1+ PROC,” said Ingmar Bruns, M.D., Chief Medical Officer. "In a patient population with a clear unmet ...