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In the leading Gubra‑Amylin NASH diet‑induced obese (GAN‑DIO) mouse model, ETX‑312 demonstrated: Dramatic improvements in NAFLD Activity Score (NAS) when administered as monotherapy or in ...
Enhanced safety: Diet-induced obesity ("DIO”) mouse model data highlighted the sufficiency of the highly-peripherally restricted CB1 inhibitor nimacimab--without central (brain) exposure--to drive ...
Title: ETX-312, a GalOmic siRNA for the treatment of MASH, effectively improves the MASH phenotype of GAN DIO-MASH mice alone or in combination with emerging therapies Poster Number: FRI-337 Date: 9 ...
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