Here we report the structure of an entire HIV-1 genome at single nucleotide resolution using SHAPE, a high-throughput RNA analysis technology. The genome encodes protein structure at two levels.

"Characterizing the structure of HIV RT was a critical turning point in ... Repetitive elements in the genome such as HERV-K are frequently overexpressed in cancer and elicit biological viral ...

Shape of things to come: Structure of HIV coat could lead to new drugs. ScienceDaily . Retrieved May 22, 2025 from www.sciencedaily.com / releases / 2009 / 11 / 091112121559.htm ...

New research on the structure of the human immunodeficiency ... But the area of the HIV RNA genome that this new research focuses on is "highly conserved." This means the rate of mutation is ...

Many people in our lab have worked to solve the structure of part of the HIV genome, which is composed of RNA instead of the DNA associated with most genomes. RNA has more flexibility than DNA ...

Integrase is one of three enzymes encoded by the HIV genome. It is a 32-kilodalton ... which makes its structure difficult to study. Although partial crystal structures are available, the full ...

Left: Structure of the Human Immunodeficiency Virus (HIV). Note the envelope protein that protects the virus against immunological detection and the small genome consisting of two short strands of ...

Regulation of the expression of the human immunodeficiency virus (HIV) genome is accomplished in ... Here we describe the crystal structure of the Tat·P-TEFb complex containing HIV-1 Tat, human ...

so knowing its structure in detail could lead us to new drugs that can treat or prevent the infection. "The capsid has to remain intact to protect the HIV genome and get it into the human cell ...

“The HIV field has missed this modification in physiological RNA structure and HIV genome for more than 30 years,” Dr. Rana noted. “I will not be surprised if other viruses with RNA genomes ...

Aug. 6 -- WEDNESDAY, Aug. 5 (HealthDay News) -- U.S. scientists have decoded the structure of an entire HIV genome, a breakthrough which could improve understanding of how the virus infects humans ...