Since the founding of the program, KOMP2 scientists have adhered to uniform phenotyping protocols, data collection, and reporting standards, made all data available via on IMPC website, and deposited ...

The Genetically Engineered Rodent Models Core possesses specialized expertise and state ... targeted knockout, and targeted knock-in mouse lines. Knockout and knock-in mouse lines can be generated ...

1997a). Many knock-out and knock-in mice have similar, if not identical, phenotypes to human patients and are therefore good models for human disease. Mouse Models Exist for Many Human Genetic ...

A new study by UCLA Health has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice.

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...