Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly offer the means to achieve significant levels of gene transfer in vivo. As the particles are often ...

Current lentiviral vector systems (the third generation) generate virus particles using four plasmids and a producer cell line. The rationale behind four plasmids is to enhance safety, as ...

better measured as the ratio between physical particles and functional viruses (p24/VCN). Conversely, another way of increasing cost-effectiveness is diminishing the amount of lentiviral vectors ...

Download this application note from Thermo Fisher Scientific to learn how scientists have used their lentiviral production system, single-use bioreactors, and clarification products to generate ...