Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...
Retroviruses are a sub-category of oncoviruses that include the lentiviruses. Retroviruses are negative single-stranded RNA viruses in which tRNA serves as a primer for the mRNA synthesis. The mRNA is ...
Among these, lentivirus-based vectors, derived from the HIV-1 retrovirus, are of growing interest in gene and cell therapy, particularly in immuno-oncology, due to their ability to infect dividing ...
They can employ either recombinant viruses, such as adenovirus, adeno-associated virus (AAV), retrovirus, or lentivirus, or non-viral platforms, such as lipid nanoparticles, to transport the chosen ...
Current projects in the laboratory focus on retroviruses, specifically the lentiviruses of humans and their primate relatives (the human and simian immunodeficiency viruses – HIV and SIV). Among other ...
Focused initially on manufacturing lentivirus and gamma-retrovirus vectors, ViroCell enables clients to start clinical trials on a scalable platform, delivering value by reducing costs ...
James Miskin brings 25 years of cell and gene therapy experience to an advisory role focused on further unlocking ViroCell's potential ViroCell Biologics ("ViroCell" or the "Company"), a cell and ...