They found i-motifs in the MYC gene family, whose activity is known to be dysregulated in around 70% of human cancers. "This presents an exciting opportunity to target disease-linked genes through ...

A new study published in Life Science Alliance reveals a key genetic connection between cancer susceptibility and tissue ...

Does MYC binding to chromatin serve transcription-independent functions, including the regulation of chromosomal integrity, gene expression, chromatin structure, cellular replication and genomic ...

Inhibiting RMB42 disrupted production of Myc proteins in pancreatic cancer cells. This approach could curtail the growth of several cancer types. A review paper published last year in European ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

Background Muscle wasting and weakness (sarcopenia) are commonly associated with COPD causing frailty and reduced quality of ...