ACB’s expertise in synthetic lethal approaches to precision oncology, MYC biology and cancer cell biology has enabled it to build a broad pipeline. Rather than focus on a single asset or one ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...