A review paper published last year in European Journal of Medicinal Chemistry characterized Myc as the “oncogene from ...

Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is ...

Lead researcher Professor Andrew Wilson explained, "Aurora-A is an incomplete kinase, which means it relies on protein ... This second interaction between N-Myc and Aurora-A is particularly ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...