Inhibiting RMB42 disrupted production of Myc proteins in pancreatic cancer cells. This approach could curtail the growth of several cancer types. A review paper published last year in European ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...