Although these were hotly debated issues at the time, it is now clear that a multitude of signal transduction pathways and numerous regulatory mechanisms have evolved to keep MYC expression under ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

Inhibiting RMB42 disrupted production of Myc proteins in pancreatic cancer cells. This approach could curtail the growth of several cancer types. A review paper published last year in European ...

This shift underscores the potential for targeting specific metabolic pathways in cancer treatment ... Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis ...