This dynamic organization is required for essential nuclear processes, such as gene expression and maintenance of genomic integrity. We study how actin operates in the nucleus to regulate nuclear ...

Recently, actin has been found to exist in the nucleus of ESCs. The team began by developing ESCs where they could visually ...

Furthermore, regulating nuclear actin dynamics could advance gene therapy, providing novel solutions for disorders characterised by nuclear fragility. “Our findings transform the way we perceive ...

Similarly, lamins are found in all cell types, where they form a meshwork that reinforces the inside of the nuclear membrane. Note that intermediate filaments are not polar in the way that actin ...