One such mechanism involves a protein called p53. Often dubbed the "guardian of the genome," this protein plays a pivotal role in ensuring that your cells grow, divide and die in an orderly fashion.

Scientists at the University of Michigan Rogel Cancer Center have found a promising new way to fight one of the most ...

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

The groups interested in studying p53 next wanted to investigate its interactions with T antigen. Scientists made these findings as the theory of oncogenes, the idea that mutated host growth-promoting ...

Shelley L. Berger, PhD, FAACR, has been recognized for her outstanding contributions to cancer research by the American Association for Cancer Research (AACR) with the 2025 AACR-Women in Cancer ...

Remarkably, all genes involved in the cell-cycle and p53 pathways in BLCA were identified as CKGs. Experiments on cell lines and a mouse model confirmed that six sensitive CKGs effectively ...