More information: Zhigang Nian et al, Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for ...

When p53 malfunctions, the result is often cancer. Learning about how p53 works has not only deepened how scientists understand cancer, but also provided promising avenues for new treatments.

Shelley L. Berger, PhD, FAACR, has been recognized for her outstanding contributions to cancer research by the American Association for Cancer Research (AACR) with the 2025 AACR-Women in Cancer ...

Stage-specific sensitivity to p53 restoration during lung cancer progression. Nature. 2010;468(7323):572-5. 5. Morris JPt, Yashinskie JJ, Koche R, Chandwani R, Tian S, Chen CC, Baslan T, Marinkovic ZS ...

PMV Pharmaceuticals, Inc. is a precision oncology company, which engages in the discovery and development of small molecule, tumor-agnostic therapies targeting p53. The company was founded by ...