Previous structures from X-ray crystallization revealed that formins are made of two identical parts that encircle the actin filament in a ring-like conformation and step along it as it grows.

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

Thin, flexible protein strands called actin filaments act like bones for our cells and are critical for its movement. Supercomputer simulations have helped solve a decades-old mystery of how actin ...

Previous structures from X-ray crystallization revealed that formins are made of two identical parts that encircle the actin ...

GAS2 is a cytoskeletal regulator that interacts with both F-actin and microtubules. Here, cryo-EM structures of GAS2 domains ...

The swinging cross bridge theory for muscle contraction envisages that the myosin cross bridge binds to the actin ... the actin filament along. This elemental event, which is part of a cycle ...

The organization and dynamics of actin filaments must be precisely controlled during these processes, and consequently defects in regulation of the actin cytoskeleton lead to various diseases ...

Our skin and mucous membranes are protected by epithelial cells, which form a barrier that defends the body from the outside ...

Gamma-actin therefore confers increased rigidity to the apical membrane, forming a network of filaments that is stronger and stiffer than that made up of beta-actin filaments. "This result is ...

Figure 6: Nucleotide-dependent processive stepping of myosin V along an actin filament. A diverse array ... 44,45 is likely to be correct for the most part. A crystal structure of the F-actin ...