I don’t think prime editing needs to wait. —Fyodor Urnov, University of California, Berkeley While working in Liu’s lab at the Broad Institute, Anzalone achieved promising gene editing results in ...

New precision genome editing technologies are transforming the therapeutic landscape for patients with certain cancers and ...

The prime editing machinery comprises a prime editing guide ... The opposite strand is nicked and repaired to match the newly edited flap, completing the edit. Anzalone AV, et al. Search-and-replace ...

Prime Medicine’s ‘search-and-replace’ genome editing technology – initially identified by gene-editing pioneers David Liu and Andrew Anzalone at the Broad Institute – has already been ...

The company was set up by gene-editing pioneers David Liu, who co-founded Editas Medicine and Beam Therapeutics, and Andrew Anzalone of the Broad Institute of MIT and Harvard University.