Most recantly researchers have pinpointed the genes that cause retinoblastoma, chronic granulomatous disease ... say experts. For most genetic diseases, the normal function of the involved gene is not ...

The two-hit hypothesis arose of out Knudson's interest in the genetic mechanisms underlying retinoblastoma, a childhood form of retinal cancer. Under normal circumstances, a population of cells in ...

Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...

This shows retinoblastoma tumor cells. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of ...

Have a family history of rare cancers, such as male breast cancer or childhood retinoblastoma. Belong to an ethnic group with a higher genetic predisposition to cancer (e.g., Ashkenazi Jewish ...

Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

MSK Kids has the world’s oldest and most successful program for treating retinoblastoma. The retinoblastoma program at MSK Kids in New York City is the world’s oldest and most successful program for ...

Retinoblastoma is a type of cancer of the eye occurring in children. Early diagnosis and treatment, and genetic counselling can go a long way in saving life and vision in children and siblings at ...