Circulating DCs are decreased in SLE; this is thought to be due to enhanced migration into peripheral affected tissues. While there is variability between in vitro studies, SLE DCs exhibit an ...

coupled with a better understanding of SLE pathogenesis, have renewed interest in this disease area. Product candidates are in development for different subcategories of SLE including lupus ...

There is a growing body of evidence linking dysregulation of the microbiome to pathogenesis in SLE, where past studies have shown decreased species diversity in favor of greater representation of ...

Understanding the cell-specific role of this molecule in SLE pathogenesis holds great promise for generating safe and effective SLE treatments. Join our April 29 webinar on promising new lupus ...