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Vaccination against herpes zoster, or shingles, was tied to significantly less dementia risk, a large-scale analysis of electronic health records in Wales showed. Receiving the live-attenuated zoster vaccine (Zostavax) reduced the probability of a new dementia diagnosis by 3.

Most previous research was conducted on cells or laboratory animals, though, or consisted of observational studies that compared people who chose to get vaccinated with those who did not in a given population.

A vaccine to fight dementia? It turns out there may already be one — shots that prevent painful shingles also appear to protect aging brains.

And over the past couple of years, observational studies have suggested that the vaccine against shingles may have a protective effect. But it's extremely difficult to do a clinical trial given that the onset of dementia may happen decades after most people first receive the shingles vaccine.

Elderly individuals inoculated with a shingles vaccine were 20% less likely to eventually receive a dementia diagnosis in the following seven years, a new study argues. The study authors based that assessment after examining the health records of about 282,

A vaccine for shingles could protect against dementia according to a new study that took advantage of a quirk in Wales' vaccine rollout scheme.