Gene expression is regulated by transcription factors in concert with epigenetic modifications (such as DNA methylation, post-translational histone modifications, the position and compaction of ...

CD4 + conventional T (Tconv) cells, or helper T cells, inspect the peptides presented by dendritic cells. If the peptides are foreign antigens, the T cells expand in numbers and transform into an ...

Tolerogenic dendritic cells in the intestines are shown to reduce the immune responses caused by exposure to food proteins.

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how ...

CD4+ conventional T (Tconv) cells, or helper T cells, inspect the peptides presented by dendritic cells. If the peptides are foreign antigens, the T cells expand in numbers and transform into an ...

Elucidation of the role of CD4+ T-helper cells and associated cytokines in the pathogenesis of CTCL has revealed a potential role for topical immune modulators in early disease. Topical imiquimod ...

Schlossman, S.F. Antigen organization regulates cluster formation and induction of cytotoxic T lymphocytes by helper T cell subsets. Proc. Natl. Acad. Sci. USA 94, 622–627 (1997).

the T cells are supposed to lay off. During an autoimmune response, the helper T cells don't distinguish between foreign peptide antigens and self-peptides properly and go on the attack no matter ...

CD4+ conventional T (Tconv) cells, or helper T cells, inspect the peptides presented by dendritic cells. If the peptides are foreign antigens, the T cells expand in numbers and transform into an ...