TGF-β plays a critical role in liver homeostasis and is considered a key driver of liver fibrosis. When TGF-β is converted from its biologically inactive form (LTGF-β) to its active form (TGF ...

Neha Dole, an assistant  professor in the departments of Physiology and Cell Biology, Orthopaedic Surgery and Pediatrics at the University of Arkansas for Medical Sciences, will speak at 12:55 p.m.

Among these factors, the transforming growth factor (TGF)-β family is important in both lineage selection and progression of differentiation of most, if not all, cell and tissue types.

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...

Several lung conditions, such as acute lung injury, require the targeted delivery of pharmacological agents to the lower lung. However, the administration of complex biologics, such as ...

Sotatercept-csrk reduced the risk of major morbidity and mortality events in adults with WHO Group 1 PAH FC 3 or 4 at high risk of mortality.

More information: Jaclynn A. Meshanni et al, Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ...

The goal of the study was to confirm whether modified NK cells had the capacity to overcome the negative effects of the TGF-β and Activin A molecules in preclinical models of HER2-positive breast ...

Combining mRNA with a specialised lipid nanoparticle could reach areas of the lungs previously inaccessible to conventional ...

Keros Therapeutics is considering whether it needs to find a buyer, while strengthening its stockholder rights as activist ...