TGF-β plays a critical role in liver homeostasis and is considered a key driver of liver fibrosis. When TGF-β is converted from its biologically inactive form (LTGF-β) to its active form (TGF ...

More information: Jaclynn A. Meshanni et al, Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ...

The goal of the study was to confirm whether modified NK cells had the capacity to overcome the negative effects of the TGF-β and Activin A molecules in preclinical models of HER2-positive breast ...

Sotatercept-csrk reduced the risk of major morbidity and mortality events in adults with WHO Group 1 PAH FC 3 or 4 at high risk of mortality.

A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and ...

The lab investigates metastatic stem cells and their stromal niches. The role of immune regulatory and regenerative signals, particularly TGF-β, is of interest. General as well as organ-specific ...