Among those genes, TP53 (encoding the p53 protein) has been identified as the most frequently mutated gene that causes cancer ...

TP53 is the gene that encodes the p53 protein. p53 refers to the protein product of the TP53 gene. The traditional view of cancer development, driven by oncogene activation and tumor suppressor ...

During a live event, Marc S. Hoffmann, MD, discussed outcomes from the SEQUOIA and ELEVATE-TN studies in chronic lymphocytic ...

In many cancer types, the TP53 gene is often mutated or deleted, which inactivates the tumour suppression activity of the p53 protein. However, loss of p53 tumour-suppressor activity can also ...

Mindrank Therapeutics (Suzhou) New Drug Research & Development Co. Ltd. has disclosed cellular tumor antigen p53 (TP53) (Y220C mutant) stabilizers reported to be useful for the treatment of cancer.