Using yeast, the researchers reveal protein interactions that could explain how the enzyme telomerase is tightly regulated to prevent cells from dividing uncontrollably or aging prematurely.

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy.

The debate continues as to whether telomerase's only function is to promote telomere extension. In recent years evidence has suggested that the enzyme promotes cancer development and might have roles ...

The long-term and durable responses observed in the Phase 3 IMerge study reinforce the practice-changing potential of telomerase inhibition as a clinically meaningful and differentiated option for ...

The analysis of the involvement of crisis in tumorigenesis has been aided by genetically defined cancer-prone mice that lack telomerase activity. These mouse models have provided insights into the ...

Continually proliferating cells maintain adequate telomeres through the action of the reverse transcriptase telomerase. Telomeres are important to human health because dysregulation of either telomere ...

You have full access to this article via your institution. So, can transformation really occur in the absence of telomerase activity or an alternative telomere-maintenance strategy? Telomerase ...

The numbers you get can be used later to determine the amount of human TERT made during this translation. Immunopurify the human telomerase with HA beads washed with 1X human telomerase buffer ( ...

While yoga is most commonly associated with flexibility and stress reduction, emerging scientific research is uncovering its ...