In 1986, T.R. Mosmann, R.L. Coffman, and colleagues observed that individual clones of helper T cells could be separated into two classes depending upon the specific cytokines the cells secrete in ...

Simultaneously they discovered the suppressive cytokine interleukin 10 inhibits antigen-presenting cells, thus regulating development of T H 1 cells. You have full access to this article via your ...

VD inhibits of Th1 cell differentiation and the production of Th1-specific cytokines. VD facilitates Treg cell generation and activity. VD has a role in the prevention of autoimmune diseases such ...