T cells may be broadly classified as either helper T cells (Th cells, CD4+) or cytotoxic T cells (Tc cells, CD8+). In 1986, T.R. Mosmann, R.L. Coffman, and colleagues observed that individual clones ...

primarily through the rapid production of anti-viral T cells. Specifically, when a virus is detected, T Helper 1 (Th1) cells are generated to facilitate an inflammatory response needed to ...

Rapa’s approach yields a T cell product with a phenotype with anti-cancer effects, including: promotion of Th1/Tc1 cytokine secretion while eliminating regulatory T cells; elimination of ...

Preclinical studies demonstrated ATI-2138’s efficacy in suppressing T cell subtypes (Th1, Th2, and Th17) linked to autoimmune and allergic diseases. The publication disclosed key findings ...