Tumor suppressor genes act as “brakes” to stop cells before they can travel down the road to cancer. A loss of function mutation in these genes can be disastrous. Like all genes, tumor ...

Here we focus on the transformation assay, which scientists first used to identify oncogenes and tumor suppressors and study their affect on cell cycle progression. Even more important will be ...

A team of University of Kentucky Markey Cancer Center researchers has found the mechanism that grants prostate cancer ...

The company’s Phase I trial found that patients remained disease free after three months utilising the lowest doses of RAG-01.

Researchers have discovered that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2 , promoting tumor growth.

Although there are tumor suppressor genes in normal cells to prevent cancer, gene mutations can cause a normal cell to become ...

Even among patients with prostate cancer liver metastasis who have a poor prognosis, elevated ctDNA fraction and tumor suppressor gene loss differentiate survival.

Shelley L. Berger, PhD, FAACR, has been recognized for her outstanding contributions to cancer research by the American Association for Cancer Research (AACR) with the 2025 AACR-Women in Cancer ...

The following is a summary of "Controversial Role Of Cd151 In Different Solid Tumors: Promoter Or Suppressor?,” published in the March 2025 issue of Cancer Cell International by Gao et al. CD151, a ...

EZH2, a core component of the Polycomb Repressive Complex 2 (PRC2), plays a fundamental role in silencing tumor suppressor genes through histone methylation. Its overexpression has been implicated ...