CAR T cells showed great cancer-killing potential, but generating these cells was cumbersome and complicated. Initially, T cell engineering depended on lentiviral or retroviral vectors to deliver ...

In perhaps the best known example, lentivirus-based vectors were instrumental to the development and recent approval of the chimeric antigen receptor (CAR) T cell therapy for a B-cell malignancy 1.

Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.

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