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"Science means constantly walking a tight rope" Heinrich Rohrer, physicist, 1933. Community-acquired pneumonia (CAP) is the leading cause of death from infectious disease worldwide and ...

Rationale The most common antibiotic used to treat people with cystic fibrosis (PWCF) is inhaled tobramycin, administered as maintenance therapy for chronic Pseudomonas aeruginosa lung infections.

2 Department of Clinical Parasitology, Hospital for Tropical Diseases, London, UK 3 Department of Respiratory Medicine, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK 4 ...

Otago and Canterbury Respiratory Research Groups, Dunedin and Christchurch Schools of Medicine, University of Otago Medical School, New Zealand Dr D R Taylor, Department of Medicine, Dunedin School of ...

Background Eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) are proteins released by activated eosinophils whose role in adult asthma remains unclear. Objective To study ...

Introduction Current bronchiectasis guidelines advise against the use of inhaled corticosteroids (ICS) except in patients with associated asthma, allergic bronchopulmonary aspergillosis (ABPA) and/or ...

Academic Unit of Respiratory Medicine, Royal Free & University College Medical School, London, UK Correspondence to: Dr J R Hurst Academic Unit of Respiratory Medicine, Royal Free & University College ...

Background We aimed to disentangle genetic and environmental causes in lung cancer while considering smoking status. Methods Four Nordic twin cohorts (43 512 monozygotic (MZ) and 71 895 same sex ...

1 Department of Paediatrics, Oxford University Hospitals NHS Trust, Oxford, UK 2 Department of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK ...

Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study ...

Background: Quadriceps weakness and loss of muscle mass predict mortality in chronic obstructive pulmonary disease (COPD). It was hypothesised that a reduced quadriceps cross-sectional area could be ...