It’s maybe the low GFR [glomerular filtration rate, a measure of kidney function] that is causing high aldosterone secretion. And the third, most important finding is that, irrespective of ...

Aldosterone is a steroid hormone secreted by the adrenal glands, which sit above the kidneys. Its main role is to regulate salt and water in the body, and so it plays a central role in controlling ...

Urinary aldosterone determinations revealed grossly elevated levels varying between 66 and 123 microgm. per day. By contrast urinary levels of 17-hydroxycorticoids and 17-ketosteroids were within ...

(HealthDay News) – For patients with heart failure with preserved ejection fraction, aldosterone blockade with spironolactone improves left ventricular diastolic function, but has no impact on ...

Aldosterone is a steroid hormone secreted by the adrenal glands, which sit above the kidneys. Its main role is to regulate salt and water in the body, and so it plays a central role in controlling ...

Lack of Suppression of Aldosterone Production Leads to Salt-Sensitive Hypertension in Female but Not Male Balb/C Mice. Hypertension, 2018; 1 DOI: 10.1161/HYPERTENSIONAHA.118.11303 ...

Higher serum aldosterone levels among patients with chronic kidney disease (CKD) are independently associated with an increased risk for CKD progression and end-stage kidney disease (ESKD ...

Mineralocorticoid receptor antagonists, particularly the most recently approved agent finerenone, should play a “central role” in the treatment of diabetic kidney disease and its related ...

Aldosterone is associated with an increased risk of chronic kidney disease progression and the development of end-stage kidney disease, according to data published in the European Heart Journal ...

Treatment with the aldosterone synthase inhibitor lorundrostat significantly decreased automated office systolic blood pressure in adults with uncontrolled hypertension in the phase 2 TARGET-HTN ...