LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

The energy invested in animal reproduction is as much as 10 times greater than previously estimated when the metabolic load of bearing and caring for offspring is accounted for, according to a new ...

Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage ...

The Lab Animal Nutrition Core (LAN) was established in 2019 to study, advise, formulate and produce lab animal diets for standard and novel animal models with translation to human health. The LAN is ...

Animal testing remains to be a vital part of modern preclinical testing. While the ethics of the use of animals in medical testing remains keenly debated, it is still generally accepted worldwide and ...

"Rodents are the most widely utilized models in biomedical research...The majority of oncology drugs that proved successful in treating tumors within rodents fail to have the same response in humans, ...