Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the ...

Cyclin-dependent kinase 6 (CDK6) bound to the inhibitor ribociclib (detail view). Enzyme involved in cell cycle regulation and target of several antitumoral drugs. 3D rendering.

It was recently shown that a single cyclin–CDK complex is sufficient to drive mitosis in fission yeast. Here, the authors show that this complex is also sufficient for meiotic progression ...

The report assesses the active Cyclin-Dependent Kinase 9 (CDK9) Inhibitor pipeline products by developmental stage, product type, molecule type, and administration route. Scope of the report: ...

High-grade glioma (HGG) is an incurable brain cancer. The transcriptomes of cells within HGG tumors are highly heterogeneous. This renders the tumors unresponsive or able to adapt to therapeutics ...

Dublin, April 15, 2024 (GLOBE NEWSWIRE) -- The "Cyclin-Dependent Kinase 9 (CDK9) Inhibitor - Pipeline Insight, 2024" clinical trials has been added to ResearchAndMarkets.com's offering."Cyclin ...

Cell division is essential for the survival of all living organisms, from the simplest yeast to complex human beings.

Indole-3-Carbinol (I3C) Inhibits Cyclin-dependent Kinase-2 Function in Human Breast Cancer Cells by Regulating the Size Distribution, Associated Cyclin E Forms, and Subcellular Localization of the ...

World Cyclin-Dependent Kinase (CDK) Inhibitors Therapeutics Pipeline Analysis 2017 - Key Players are Eli Lilly and Company, Merck & Co. & AstraZeneca - Research and Markets November 27, 2017 11:20 ...

CDK inhibitors are a type of cancer treatment - a drug such as the ones given during chemotherapy - to block this activity, inhibit this cell division, and slow the growth and spread of cancer cells.

Researchers from Incyte Research Institute presented the discovery of a cyclin-dependent kinase 2 (CDK2) inhibitor, INCB-123667, being developed for the treatment of cyclin E dysregulated cancers.