Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

Now, a new study reveals that this pivotal step in human development is guided by a precise interplay between chemical ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

Animal development consists of a cascade of tissue differentiation and shape change. Associated mechanical signals regulate tissue differentiation. Here we demonstrate that endogenous mechanical cues ...

Gastrulation, a prerequisite for organogenesis, begins with the formation of the primitive streak (PS), where epiblast cells experience an epithelial-to-mesenchymal transition (EMT) to exit the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 23 (June 8, 2021), pp. 1-10 (10 pages) Markers for the endoderm and mesoderm germ layers are commonly ...

Platelet-derived growth factor (PDGF) signaling is essential for processes involving cell motility and differentiation during embryonic development in a wide variety of organisms including the mouse, ...

In a recent study published in the Cell journal, researchers showed that post-gastrulation synthetic embryos (sEmbryos) could be synthesized outside the uterus using mouse naïve embryonic stem cells ...

Alaniz Emig A, Williams MLK. Generation of Naïve Blastoderm Explants from Zebrafish Embryos. J Vis Exp. 2021 Jul 30;(173). doi: 10.3791/62797. PMID: 34398141. View article Williams ML, Solnica-Krezel ...

When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...