It’s one of life’s most defining moments—that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for ...

Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...

At this stage, known as gastrulation, a flat and featureless sheet of cells folds into a living blueprint for the body, a fleeting transformation into axes and layers that will determine how every ...

Jay Shendure is in the Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA, and at the Brotman Baty Institute for Precision Medicine, the Allen Discovery Center for ...

The new platform's ethically grounded approach promises to reveal much about how human embryos form during the earliest stages of pregnancy. It's one of life's most defining moments -- that crucial ...

Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a 'black box' of human development. This is because human embryos are ...

Gastrulation is a process common to nearly all metazoan organisms during which an embryo with distinct tissue layers develops out of a seemingly unstructured assembly of cells referred to as 'blastula ...

Gastrulation is one of the most intensely studied biological processes. During gastrulation, animal embryos undergo tissue flows and folding events that transform a simple monolayer of cells into a ...

In a recent study published in the Cell journal, researchers showed that post-gastrulation synthetic embryos (sEmbryos) could be synthesized outside the uterus using mouse naïve embryonic stem cells ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, No. 18 (Sep. 15, 1992), pp. 8736-8740 (5 pages) To study the role of keratin filaments in Xenopus development, ...