New data from Eurofins Discovery show that Telomir-1 blocks enzymes that drive disease by turning off critical genes-highlighting its potential to treat cancer, autoimmune conditions, ...

CNSide® can quantify leptomeningeal metastases (LM) over time and monitor changes in the expression of multiple targetable ...

Neuroblastoma is the most common solid tumor in infants and accounts for nearly 15% of all pediatric cancer-related deaths.

Finally, for preclinical research, Histobiolab's xenograft and chimeric model analysis services rapidly and accurately identify the presence of cross-species cells in models, providing a critical ...

We observed that more than 50% of 2,024 advanced UC tumors demonstrated some degree of HER2 protein expression detected using a standardized IHC method, whereas about 12% of specimens had ERBB2 gene ...

Human epidermal growth factor 2 (HER2/ERBB2) has recently become a pan-tumor–agnostic target after the approval of trastuzumab deruxtecan for solid tumors with HER2 overexpression (3+). HER2 ...

The amplified resistance gene in E. coli, named blaTEM-1, produces a beta-lactamase enzyme that breaks down the antibiotic piperacillin.

Targeted genomic editing made great strides in recent decades, especially thanks to the advent of endonuclease-based gene-editing systems such as CRISPR-Cas9. However, targeted insertion of larger ...

Gene amplification is associated with an increase in copy number of a gene within a cellular genome. 9 This phenomenon leads to increased gene expression, which may increase cell growth.