Finally, for preclinical research, Histobiolab's xenograft and chimeric model analysis services rapidly and accurately identify the presence of cross-species cells in models, providing a critical ...

We observed that more than 50% of 2,024 advanced UC tumors demonstrated some degree of HER2 protein expression detected using a standardized IHC method, whereas about 12% of specimens had ERBB2 gene ...

Targeted genomic editing made great strides in recent decades, especially thanks to the advent of endonuclease-based gene-editing systems such as CRISPR-Cas9. However, targeted insertion of larger ...

CNSide® can quantify leptomeningeal metastases (LM) over time and monitor changes in the expression of multiple targetable ...

The amplified resistance gene in E. coli, named blaTEM-1, produces a beta-lactamase enzyme that breaks down the antibiotic piperacillin.

Human epidermal growth factor 2 (HER2/ERBB2) has recently become a pan-tumor–agnostic target after the approval of trastuzumab deruxtecan for solid tumors with HER2 overexpression (3+). HER2 ...

Gene amplification is associated with an increase in copy number of a gene within a cellular genome. 9 This phenomenon leads to increased gene expression, which may increase cell growth.

Neuroblastoma is the most common solid tumor in infants and accounts for nearly 15% of all pediatric cancer-related deaths.

New data from Eurofins Discovery show that Telomir-1 blocks enzymes that drive disease by turning off critical genes-highlighting its potential to treat cancer, autoimmune conditions, ...