News Release 28-May-2025 Intestinal bacteria influence aging of blood vessels Peer-Reviewed Publication University of Zurich Cardiovascular diseases are the most common cause of death worldwide.

Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury. Cell Stem Cell, 2022; 29 (8): 1262 DOI: 10.1016/j.stem.2022.07.007 ...

In several series of experiments, Saeedi's team was able to prove that phenylacetic acid leads to senescence of endothelial cells, in which the cells that line the inside of blood vessels do not ...

"This discovery showed us that lymphatic endothelial cells are a key component of the intestinal niche and essential for intestinal repair after cases of damage, like chemotherapy," said Klein ...

DHHC5 mediates the palmitoylation of CRYBG1, an actin-binding protein, thereby regulating the localization of VEGFR2 in lipid rafts of lymphatic endothelial cells (LECs).