Bcl10 is an intracellular protein essential for nuclear factor (NF)-κB activation after lymphocyte antigen receptor stimulation. Using knockout mice, we show that absence of Bcl10 impeded conversion ...

In ADA suits, courts often have to decide what constitutes an essential job function, as the law sometimes requires that employers remove marginal function as an accommodation, but not essential ...

In a recent opinion by the Eleventh Circuit Court of Appeals involving a Type-1 insulin-dependent diabetic, the court found that passing a Department of Transportation medical examination was an ...

Cells are selected to differentiate into these two subsets based in part on the strength of B cell receptor (BCR) signalling in individual cells. Stronger BCR signals favour the development of ...

Courts often give deference to employers when it comes to essential functions. This determination is relevant in ADA claims because the law doesn't require that employers remove essential functions as ...

Andrew Bloomenthal has 20+ years of editorial experience as a financial journalist and as a financial services marketing writer. Erika Rasure is globally-recognized as a leading consumer economics ...