A first-in-human study suggests that tirzepatide modulates abnormal activity in the brain’s nucleus accumbens, reducing food cravings and inducing weight loss in severe obesity.

The nucleus accumbens is a tiny element of the human brain triggered when we experience something enjoyable, and used to help ...

The nucleus accumbens is a tiny element of the human brain triggered when we experience something enjoyable, and used to help us learn behaviours that lead to rewards.

The study, published in Biological Psychiatry: Global Open Science, found the effect occurs in the paraventricular nucleus of ...

A new study has identified a specific brain circuit that can push behavior into a compulsive “repeat mode,” forcing mice to continue digging and sniffing even when rewards are available.

New research uncovers the exact immune-to-brain pathway that drives the loss of social motivation during sickness.

Deep Brain Stimulation (DBS) is an invasive treatment. Pairs of electrodes are surgically implanted in the brain and connected to a pulse generator placed under the skin on the chest. DBS-nbM delivers ...