Cells were washed in PBS+1% FBS and incubated for 30 minutes at 37°C with CCR7-BV421 (Biolegend ... CD27-BV480 (BD), CD38-APC/Fire810 (Biolegend), CD56-BUV737 (BD), CD16, CD45RA-BUV395 (BD), ...

Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced ...

“The CD45 gene produces multiple isoforms through alternative splicing, notably CD45RA and CD45RO. These isoforms are not interchangeable, they mark functionally distinct T cell states: CD45RA is ...

Objective: Primary Sjögren’s syndrome (pSS) and Hashimoto thyroiditis (HT) can occur in the same patient population, but the mechanism of co-occurrence remains unknown. This study aims to explore the ...

3 German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany 4 Computational Biology for Individualised Medicine, ...

The adaptive immune system is a highly specific, coordinated response involving specialised immune cells, with most of these being T cells. T cells are a vital part of the immune response to infection ...