However, some people are born with a mutation—a small change—in their calmodulin protein. This rare condition leads to what scientists now call “calmodulinopathies,” which are serious and often deadly ...

DelveInsight's "LUPKYNIS Market Size, Forecast, and Market Insight Report" highlights the details around LUPKYNIS, the first ...

As a novel calcineurin inhibitor with proven efficacy in improving renal outcomes, LUPKYNIS addresses a high unmet medical need. With increasing awareness, supportive guidelines, and potential ...

Figure 1: a, Shift in calmodulin-associated CnA isoforms in the failing human left ventricle. Of the three calcineurin A isoforms (α, β and γ), CnA-β predominates in cardiac muscle.

In the recent article, “Antisense Oligonucleotide Therapy for Calmodulinopathy,” we provided the first proof-of-concept in ...

Department of Mathematics, Michigan State University, East Lansing, Michigan 48824, United States Department of Mathematics, Michigan State University, East Lansing, Michigan 48824, United States ...

Department of Endocrinology and Metabolism, Affiliated Hospital of Qingdao University, Qingdao 266003, P. R. China Qingdao Key Laboratory of Thyroid, Diseases, Medical Research Center, Qingdao 266555, ...

Correspondence to Professor Arthur A M Wilde, Amsterdam Universitair Medische Centra, Amsterdam, The Netherlands; a.a.wilde{at}amsterdamumc.nl Congenital long QT syndrome (LQTS) is characterised by ...

Graduate Program in Translational Biology, Medicine, and Health (R.L.P., G.A.B., K.E.S., D.R.K.), Virginia Tech, Blacksburg. Fralin Biomedical Research Institute at ...

1 The First School of Clinical Medicine, Lanzhou University, Lanzhou, China 2 Key Laboratory of Brain Science, Key Laboratory of Anesthesia and Organ Protection of Ministry of Education (In ...

Buchmann Institute for Molecular Life Sciences, Goethe-University, Frankfurt am Main, Germany Institute for Biophysical Chemistry, Department of Biochemistry, Chemistry, and Pharmacy, ...