promoted cell apoptosis, and triggered G0/G1 cell cycle arrest. Further analysis demonstrated a dose-dependent reduction in c-Myc expression following ZW27941 treatment, which implicates the ...

Researchers describe a concentric supraparticle system that protects and delivers RNA therapeutics for gene silencing in ...

Abstract 1679, under the session ‘Drug Combination Strategies for Cancer Treatment’, showed that APG-2449, a novel focal adhesion kinase (FAK) inhibitor, enhances the anti-tumour activity of ...

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while promoting cell cycle arrest at the G0/G1 phase and inducing apoptosis. Mechanistically, exosomal lnc-TAF12–2:1 acted as a sponge for miR-7847–3p, alleviating miRNA-mediated silencing of ...

This useful study explores the role of RAP2A in asymmetric cell division (ACD) regulation in glioblastoma stem cells (GSCs), drawing parallels to Drosophila ACD mechanisms and proposing that an ...

Two small clinical trials revive hope for an old idea: Cells injected into the brain might replace the nerve cells that die in Parkinson’s disease. The studies, published April 16 in Nature ...

Scientists create hydrogel that 'reprograms' cancer cells into stem cells in 24 hours Prof. Shinya Tanaka of Hokkaido University led the research on double network (DN) hydrogels, which help turn ...

When this happens, not only do your brain and ears perceive it, but your cells may also. Technically speaking, sound is a simple phenomenon, consisting of compressional mechanical waves ...