A longtime Tulsa doctor who filed an appeal with the Oklahoma Supreme Court to get his medical license back said he will not seek reinstatement as a doctor if the appeal fails. Walter Jay Exon ...

which have all bagged regulatory approvals for oral therapies that target NSCLC harbouring a specific mutation in Met known as exon 14 skipping which affects about 3% to 4% of NSCLC patients.

Zipalertinib shows promising efficacy and safety for advanced NSCLC with EGFR exon 20 mutations, offering a much-needed oral treatment option. For patients with advanced non–small cell lung cancer ...

Following lackluster data from a Phase 2 clinical trial, Pepgen will discontinue developing PGN-ED051, its experimental exon 51-skipping therapy for Duchenne muscular dystrophy (DMD). The company said ...

This complex protects 8 nucleotides of mRNA from complete RNase digestion at a conserved position 20–24 nucleotides upstream of exon–exon junctions. Splicing‐dependent RNase protection of this region ...

These mutations can result in either complete skipping of the exon, retention of the intron, or the introduction of a new splice site within an exon or intron. Sometimes mutations that do not disrupt ...

1 Department of Nephrology, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, China 2 Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, ...