Western blot assays were performed to identify the presence of p53, phospho-p53, and murine double minute 2 (MDM2) isoforms in plasma samples. Densitometric analysis was used to determine the ...

The small molecules in question are ASTX029, an ERK1/2 inhibitor that has completed a phase 2 study, and ASTX295 an MDM2 antagonist that has undergone a phase 1 trial. Both candidates have ...

An increase in shark sightings at an Adelaide beach has prompted a warning from authorities ahead of the Easter long weekend. AddedApr 17th, 2025 The state government is planning to send ...

In oncology, she highlighted MDM2-p53 antagonist brigimadlin, which has advanced into a pivotal trial for dedifferentiated liposarcoma, a rare cancer with limited treatment options so far ...

Mysuru’s favorite and largest circulated English evening daily has kept the citizens of Mysuru informed and entertained since 1978. Over the past 45 years, Star of Mysore has been the newspaper that ...

Binance will temporarily halt KDA deposits and withdrawals on April 29 for a smooth update. The upcoming network upgrade will enhance network performance and scalability. A confirmed falling wedge ...

The first-ever “Food is Medicine” community roundtable between the KDA and the KHA took place Wednesday at Baptist Health Deaconess in Madisonville. Led by Shell, it brought together local leaders ...

Background: Aminoglycosides (AGs) are one of the initial classes of antibiotics that have been used clinically and possess broad spectrum of activity. Nevertheless, their clinical utilization is ...