This immune activation is characterized by increased production of pro-inflammatory cytokines such as IL-6, IL-1β, TNF-α ... Elevated levels of senescence markers such as p16, p21, and β-galactosidase ...

The CARD domain of ASC can then interact with the CARD domain of pro-caspase-1 to facilitate the maturation of IL-1β, IL-18, and GSDMD ... Specifically, it upregulates p21 while downregulating cyclin ...

Grand Theft Auto 85 new GTA 6 screenshots and images drop alongside new trailer, providing an in-depth tour of Vice City and all its surrounding locations Grand Theft Auto GTA 6 map returns to ...

Mammary gland fibroblasts are highly plastic and transition through distinct states during development and disease. A new ...

"He doesn’t come out of baseball games, so we put him on the IL," Roberts said Tuesday ... but leading the majors in both wins and win percentage (68.6%). They also recalled right-handed ...

The new trailer for the highly anticipated video game teases more of the story and mayhem that awaits players in “GTA 6,” which was recently delayed to May 26, 2026. It shows the dual ...

UPDATE: Before Monday’s game against the Arizona Diamondbacks, Mets manager Carlos Mendoza told reporters that DH Jesse Winker will miss 6-8 weeks with ... looks like an IL situation,” Mendoza ...

Battlefield 6 is emphasizing destruction as a major tactical tool. Not only can you breach into rooms, but rubble from destructed environments will remain on the ground throughout the match to ...