VD inhibits the polarization of naive T0 cells to T1 and to a lesser extent T2 cells (5.1.), it shifts the balance of Th1/Th2 T cells toward the latter ones (5.2.) and upregulates Treg cells ...

Myasthenia gravis (MG) is a rare, chronic autoimmune disorder that disrupts the communication between nerves and muscles. It ...

After encountering antigen in the periphery and under the influence of the cytokine milieu present, CD4 + T cells can further differentiate into subtypes, including Th1, Th2 and Th17. T cells seem ...

This collaboration supports the development of multiple Treg cell therapy drug candidates targeting severe immune disorders. AGC Biologics will provide lentiviral vector (LVV) material using its ...

Americans are increasingly critical of Elon Musk’s role in the Trump administration, with a Washington Post-ABC News-Ipsos poll finding negative reactions to some cuts made by his U.S. DOGE ...

Here we address how microbiota development in infants is affected by mode of delivery, and relate differences in colonisation patterns to the maturation of a balanced Th1/Th2 immune response. Design ...

CD4 + type 2 helper T (Th2) cells facilitate the adaptive immune response through the secretion of cytokines such as IL-4, IL-5, and IL-13. While the Th2 program is governed by the transcription ...

Unravelling Treg Biology, Pioneering Best-in-Class Approaches & Demonstrating Clinical Efficacy to Advance Validated Therapeutic Options in Autoimmunity, Inflammation & Beyond ...