(C-D). The half-life of nsp16 was prolonged by the proteasome ... The whole-cell lysates were incubated with anti-Flag beads and used for IB with anti-Myc or anti-Flag antibodies to detect the ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

As recently as March, the FDA approved the IL-23 inhibitor guselkumab (Tremfya, Johnson & Johnson/Janssen) for patients with Crohn’s disease, offering both IV and subcutaneous induction options.

I think I might have more energy, too, and am more motivated. I can’t say if it’s done any “anti-ageing” magic yet. But both I and experts seem to agree that strength training, combined ...

ROTTERDAM, Netherlands (AP) — A gleaming spiral staircase jutting from the roof of a former Dutch warehouse overlooks the waterway where millions of Europeans once boarded ships bound for a new ...

The approval marks the second international approval for rozanolixizumab (Rystiggo; UCB Pharma) for generalized myasthenia ...

In Europe, these therapies were introduced between 2006 and 2013. The anti-TNF era was followed by the emergence of interleukin (IL) inhibitors, with J&J’s Stelara (ustekinumab) leading the way ...

St Kilda great Nick Riewoldt has called on the AFL to introduce anti-tampering rules to stop contract talks “destabilising careers”. West Coast captain Oscar Allen is enduring a lame-duck final year ...

SERPINB9 (SPB9) has been reported as a critical factor in the resistance to immunotherapy but its role in chemosensitivity remains unknown. Here this work reports that gemcitabine (GEM) treatment ...

Before taking any medication, as an athlete you must check the status on the List or with your anti-doping organization (ADO). If the substance is prohibited, you will need to follow the process to ...

Department of Pediatric and Preventive Dentistry, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, China ...